Diabète et complications infectieuses : étude réalisée au Centre Hospitalier Universitaire de Kamenge à propos de 36 cas
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Date
2021-09
Journal Title
Journal ISSN
Volume Title
Publisher
Médecine d’Afrique Noire
Abstract
Diabetes and infectious complications: A study of 36 cases at the Kamenge University Teaching Hospital
Introduction: Diabetes is associated with a high risk of infections, mainly bacterial. This is believed to be linked to the detrimental effect of hyperglycemia on cellular immunity. These infections are grafted with a heavy morbidity and mortality in this population. The aim of this study is to determine the clinical profile of the diabetic population studied, and to specify the epidemiological, clinical and evolutionary characteristics of the diagnosed infections.
Patients and methods: This is a cross-sectional descriptive and analytical study on 36 diabetic patients (24 men and 12 women) admitted to the internal medicine and surgery departments of the Kamenge UTH for infectious complications, carried out on the period from April 1st to June 30th, 2020.
Results: The mean age of our patients was 53.5 ± 14.7 years. Fourteen patients had type 1 diabetes and twenty-two had type 2 diabetes. The mean duration of diabetes was 10.5 years. Eight patients had inaugural diabetes discovered during the infectious complication. The mean HbA1C was 8.47 ±0.82% with extremes of 7 and 10%. The diagnosed infections were, in order of decreasing rate of cases, pulmonary in 33.3%, skin in 30.6%, urinary in 27.8%, digestive in 13.9% and 13.9% of cases of malaria. The outcome was good under antibiotic and/or anti-malaria treatment, combined with anti- diabetic treatment for high blood sugar. Nevertheless, an amputation was performed in one patient
and a case of death was recorded.
Conclusion: Unbalanced diabetes, the case of all our patients, promotes the development of infections, and intercurrent infections can decompensate diabetes. A prevention based on strengthening the education of the diabetic patient as well as early and appropriate management of the infected patient by a multidisciplinary team must be essential.
Description
Article de recherche